Team

Assistant Professor of Ophthalmology, Harvard Medical School

Assistant Scientist, Ocular Genomics Institute, Massachusetts Eye and Ear (MEE)  

Co-Director, Biostatistics and Bioinformatics Core, MEE

Associate Member, Broad Institute of Harvard and MIT

Member of the Genotype-Tissue Expression (GTEx) Project Consortium

E-mail: ayellet_segre [at] meei.harvard.edu

B.S., Biology and Data Sciences, College Of Charleston, Charleston, SC

Katherine is interested in integrating human genetics, functional genomics, and small molecule perturbational expression profiles to identify new drug repurposing opportunities for complex eye diseases, such as glaucoma and age-related macular degeneration.

M.Sc., Bioinformatics, Northeastern University, Boston, MA

B.S., Biotechnology, Dayananda Sagar College of Engineering, Bengaluru, India

Puja is interested in using splicing QTLs in human retina to identify novel regulatory mechanisms that lead to age-related macular degeneration, and in integrating functional genomic and single cell data with GWAS to shed light on the causal mechanisms of eye disease.

M.Sc. student in Biomedical Informatics Program, Harvard Medical School

B.A. in Computational Biology; Mathematical Sciences: Statistics, Colby College, Waterville, ME

B.Sc. in Biochemistry and Molecular Biology; University of Wisconsin - Eau Claire

B.Sc. in Molecular and Cellular Biology, Harvard College

Ph.D., Integrative Genetics and Genomics, University of California Davis

B.S., Chemistry with emphasis in Biochemistry and Molecular Biology, Universidade de Sao Paulo, Brazil

Ph.D., Biomathematics, NC State (North Carolina State University) 

M.Sc., Applied Mathematics, NC State University

B.S., Applied Mathematics, Marist College Biology and Computer Science 

Ph.D., Biology, University of Houston

B.Tech. in Biotechnology, Kathmandu University, Nepal 

M.Sc. in Bioinformatics, Johns Hopkins University

PharmD, Jawaharlal Nehru Technological University, India

B.Sc., Biochemistry/Molecular Biology and Data Science at Fisk University (Junior)

B.Sc. in Neuroscience and minor in Computer Science at Reed College (Senior)

M.Sc., Bioinformatics Program at Boston University

B.A., Biochemistry and Molecular Biology; Minor in Mathematics, The College of Wooster, Wooster, Ohio

M.Sc., Bioinformatics, Northeastern University, Boston, MA

B.Sc., Premedical and Health Studies, MCPHS University, Boston, MA

Ph.D., Statistics, Australian National University, Australia

M.Sc.., Statistics, Australian National University, Australia

B.S., Mathematics, Capital Normal University, China 

M.D., Harvard and MIT Health, Sciences and Technology (HST) MD Program

Ph.D., Biological Engineering, MIT

B.S., Materials Engineering, Ohio State University, Columbus, OH

Co-mentored with Prof. Janey Wiggs, Mass. Eye and Ear, HMS

Jackie is using soft clustering analysis (non-negative matrix factorization) across genetic associations of known glaucoma loci with multiple endophenotypes of primary open angle glaucoma to identify pathogenic mechanisms and biological subtypes of glaucoma.

M.Sc. in Bioinformatics Program at Boston University

B.S. in Biotechnology, JECRC University, Jaipur, Rajasthan, India

M.Sc., Bioinformatics, Northeastern University, Boston, MA

B.E in Biotechnology, SIES Graduate School of Technology, Mumbai, India